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      Chinachemnet   |   Sign in   |   Join NowColistin Sulphate Manufacturers, China Colistin Sulphate Suppliers, China Colistin Sulphate Exporters
      • Region :Pharmaceuticals and Biochemicals/Antibiotic and antimicrobial agents
      • Tel : +86-571-88219588
      • Fax : +86-571-88210515
      • Email :sunny@sunnybiotech.com
      • URL :www.sunnybiotech.com

      Details for China Colistin Sulphate

      Colistin Sulphate 1264-72-8

      Category :

      Pharmaceuticals and Biochemicals/Antibiotic and antimicrobial agents

      Colistin Sulphate
      CAS NO : 1264-72-8
      EC NO : 215-034-3
      MF : C52H98N16O13
      MW : 1155.4339
      Specification : EP / CP
      Packing : 25kg drum
      Product description :

      Colistin Sulphate

       

       Colistin (Polymyxin E) is polymyxin antibiotic isolated from culture fluid of Bacillus polymyxa var colistinus bacteria in soil. Colistin is effective against most Gram-negative bacilli such as E-coil, Serpulina Hyodysenteriae, Salmonella Pullorum  and also effective on Pseudomonas aeruginosa.

       

      [Molecular Formula]    2(C52H98N16O13) · 5(H2SO4

       

      [Molecular Weight]      2801.27

       

      [Specifications for EP7] 

       

      Test Items

      Specifications

      Appearance

      White or almost white, hygroscopic powder

      Specific Rotation

      -63º to -73º

      Identification

      Positive

      pH

      4.0 to 6.0

      Loss on Drying

      3.5% max

      Sulphate (Dried Basis)

      16.0 to 18.0 %

      Sulphated Ash

      1.0% max

      Total Impurities

      23.0% max

      Assay HPLC (Dried Basis)

      Sum of E1,E2,E1-I,E1-7MOA,E3

      77.0% min

      Potency (Dried Basis)

      19,000 IU/mg min

       

       

      [Characteristic]

       

        1)  Improve growth performance and conversion rate of livestock & poultry;

        2)  Inhibit Gram-negative bacteria at growth duration or dormancy state;

        3)  Prevent bacterial diarrhea & synergistic effects with other antibiotics;

        4)  No cross tolerance with broad range of antibacterial agent;

        5)  Little absorbed by intestine and stomach, no residue.

       

       [Recommended dosage]   g/ton of complete feed

      Target Animals

      Colistin Sulphate

      Withdrawal Period

      Swine

      <2 months

      2(60MU) – 20(600MU)

      7 Days

      2-4 months

      2(60MU) – 40(1,200MU)

      Poultry

      < 70 days

      2(60MU) – 20(600MU)

      Cattle

      < 3 months

      5(150MU) – 40(1,200MU)

      Note: 1ug of Colistin is equivalent to 30 units of Colistin; MU = Million Unit

       

       [Precaution] 

       1)   May cause damage in kidney function by overdosing;

       2)  Prohibited to use during laying period. 

       

       [Storage]   It should be kept cool and dry in well-closed original package.

       

       [Package]   25kg Drum net each

       

       [Shelf Life]   Two Years

      Uses : Antibiotic for Animal Use
      Synonyms : Colistin Sulphate;n-[3-amino-1-[[1-[[3-amino-1-[[6,9,18-tris(2-aminoethyl)-3-(1-hydroxyethyl)-12,15-bis(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclotricos-21-yl]carbamoyl]propyl]carbamoyl]-2-hydroxy-propyl]carbamoyl]propyl]-5-methyl-heptanamide sulfate;N-[(2S)-4-amino-1-{[(2S,3R)-1-{[(2S)-4-amino-1-oxo-1-{[(3S,6S,9S,12S,15R,18S,21S)-6,9,18-tris(2-aminoethyl)-3-[(1R)-1-hydroxyethyl]-12,15-bis(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptaazacyclotricosan-21-yl]amino}butan-2-yl]amino}-3-hydroxy-1-oxobutan-2-yl]amino}-1-oxobutan-2-yl]-6-methyloctanamide sulfate (1:1);N-[(1S)-3-amino-1-{[(1S,2R)-1-{[(1S)-3-amino-1-{[(3S,6S,9S,12S,15R,18S,21S)-6,9,18-tris(2-aminoethyl)-3-[(1R)-1-hydroxyethyl]-12,15-bis(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptaazacyclotricosan-21-yl]carbamoyl}propyl]carbamoyl}-2-hydroxypropyl]carbamoyl}propyl]-5-methylheptanamide;belcomycin;
      Molecular Structure : Colistin Sulphate 1264-72-8
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